Several epidemiological studies suggest covariation between seafood
consumption and rates of mood disorders. Biological marker studies indicate deficits in omega−3 fatty acids in people with depressive
disorders, while several treatment studies indicate therapeutic
benefits from omega-3 supplementation. A similar contribution of
omega-3 fatty acids to coronary artery disease may explain the
well-described links between coronary artery disease and depression.
Deficits in omega-3 fatty acids have been identified as a contributing
factor to mood disorders and offer a potential rational treatment
approach.